Set oven to 300 degrees Fahrenheit. Low temperature helps brisket cook slowly and become tender.

Mix smoked paprika, salt, pepper, garlic powder, onion powder and chili powder in a small bowl.

Rub spice mixture over the entire brisket evenly. Press gently so seasoning sticks well to meat.

Place a large skillet on medium-high heat. Add olive oil and let it heat properly.

Sear brisket for several minutes on each side until deep brown crust forms beautifully.

Place sliced onions and minced garlic in roasting pan. They create flavor and moisture while cooking.

Transfer seared brisket into roasting pan carefully. Place it directly over onions and garlic.

Mix beef broth, barbecue sauce, Worcestershire sauce and brown sugar together in a bowl.

Pour sauce mixture over brisket evenly. This keeps the meat juicy and flavorful during roasting.

Cover roasting pan tightly with foil. Bake for about 4 hours until brisket becomes fork-tender.

Remove brisket from oven and let rest for 15 minutes before slicing for juicy results.

Slice brisket against the grain carefully. Spoon extra sauce over top before serving warm.